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The Canadian Urinary Bladder Survey shows that about 43% of men and 57% of women are affected by lower urinary tract symptoms, such as nocturia (frequent nighttime urination), overactive bladder (OAB), and urination urgency. (1)
Weakening of the bladder and the sphincter muscle that controls the release of urine is typically an issue for people over the age of 40, and becomes increasingly common in older age. (1) Men and women are afflicted with bladder irritation for different reasons. For women, weakening of the pelvic floor muscles and bladder sphincter can make it more difficult to control urine flow. (2) Men may be affected by the enlargement of their prostate gland, which compresses the urethral canal. (3)
Pumpkin seed has been traditionally used in herbal medicine throughout Europe as a remedy for urinary problems associated with an enlarged prostate gland and irritable bladder. (4) It is approved by the German Commission E as a therapeutic agent for these conditions. (5) The underlying mechanisms behind pumpkin seeds’ benefits are not entirely clear. From a nutritional standpoint, pumpkin seeds contain amino acid precursors for nitric oxide, which is needed to relax the urination muscles and decrease pressure in a full bladder. (4)
In a randomized, double-blind, placebo-controlled study, women diagnosed with OAB were supplemented with a combination of 875 mg of pumpkin seed extract and 125 mg of soy germ extract per day for 12 weeks. Significant improvements in OAB symptoms were identified, in addition to improvements in daily urination frequency, urgency, incontinence, and nighttime urination, compared to baseline measurements. (6) Compared to the placebo group, supplementation was most significant for measures of daily urination frequency and urgency, and frequency of nighttime urination. (6)
A clinical trial was conducted on women ages 35–84 who reported symptoms of stress incontinence, such as urination during physical movements, coughing, or sneezing. Women were supplemented with a total daily dose of 875 mg of pumpkin seed extract and 164 mg of soy germ extract. After six weeks, the total rate of improvement was 87.5%, with 27.1% of participants identified as “markedly improved.” By the end of the trial, women were experiencing 68% fewer episodes of stress incontinence per day than before supplementation. (7)
Recommended adult dose: First 2 weeks: 1 capsule 3 times daily or as directed by a health care practitioner. After the first 2 weeks: 1 capsule 2 times daily or as directed by a health care practitioner.
Caution: Consult a health care practitioner prior to use to exclude a diagnosis of prostate cancer, or if you are pregnant or breastfeeding. Consult a health care practitioner in cases of blood in the urine or acute urine retention, or if symptoms persist or worsen. Hypersensitivity (allergy) has been known to occur, in which case discontinue use. Do not take if you are allergic to Cucurbita species. Keep out of reach of children.
What does this product do?
Aging individuals frequently encounter a weakening of the bladder and the bladder sphincter muscle (which controls the release of urine). Studies have demonstrated that by taking Water Soluble Pumpkin Seed Extract, as found in Brad King's Ultimate Bladder Control, significantly improves the structural support of the bladder AND the function of the sphincter muscle. Conclusions from a human clinical trial demonstrated that Water Soluble Pumpkin Seed Extract significantly increased maximum bladder capacity while decreasing urination frequency.
How does water soluble Pumpkin Seed Extract work?
Water soluble pumpkin seed extract performs a tissue building effect on the pelvic floor muscles in 3 ways:
1/ by inhibiting the enzyme "aromatase", so there is a higher level of circulating testosterone available to strengthen the pelvic muscles
2/ by binding to the androgen receptor on the wall of the pelvic muscle cells and thereby inducing a strengthening effect
3/ by increasing Nitric Oxide synthesis and thereby supporting the healthy function of the bladder muscle and bladder sphincter muscle.
Is Ultimate Bladder Control gluten free?
Yes, we do have confirmation on file that there is no gluten added and no gluten present in Ultimate Bladder Control. However, our manufacturing facility is NOT a gluten free facility, and as we do process products that contain gluten we are unable to confirm 100% that there is no possibility of cross contamination.
Are Brad King's products WADA certified?
No, we do not have an official WADA (World Anti-Doping Agency) designation or release on our Ultimate products by Brad King.
Do all of your products have an NPN?
Yes, all of our products have been issued a Natural Product Number (NPN) by Health Canada – these numbers do appear on our labels. Further Natural Health Product criteria and information can be found on the Health Canada website www.hc-sc.gc.ca Under the Food and Drugs Act items that are considered a food – for example, our protein powders and herbal teas – do not require an NPN. Are your capsules GMO free?
Yes, our vegetarian capsule shells, our gelatin capsule shells and our softgel shells are all non-GMO.
Are your products GMO free?
Preferred Nutrition is currently in the process of testing all of our products so that we can advise the public if any of them contain ingredients that come from genetically modified organisms or not. Once the testing is complete we will indicate on our website, as well as on our product information sheets and on our labels. This will be done as quickly as possible and on a product-by-product basis.Why have your cautions and your recommended/suggested usages changed so dramatically on many of your labels?
The changes you are noticing to our suggested usage and cautionary statements have been at the directive of Health Canada. There have been many regulatory changes with regards to Natural Health Products causing companies to change their labels accordingly. We update our website, product information sheets and labels on the actual products to reflect these regulations as quickly as we possibly can. Health Canada and the industry representing natural health products act according to the interest of consumers and their safety. As a result, if there is any concern with an existing condition, a caution is added to advise the consumer to seek out feedback from their Health Care professional. Will this product help me lose weight?
There is no such thing as a "magic" pill or product - the only way to succeed (and maintain) true weight loss is by adopting a healthy lifestyle combining adequate exercise and proper nutrition. If you are concerned about poor eating habits or cravings, then we recommend you seek advice from a Nutritionist or Naturopath to obtain some guidance on healthy eating, as well as to investigate possible underlying (or undiagnosed) hormonal imbalances, which can make it harder to lose weight. You might also want to consider speaking with a personal trainer to help you discover a fun fitness program that you enjoy - because, no matter what, in order to achieve and maintain any type of weight loss, exercise is required. Our vitamins and supplements are designed to help you in your quest to a daily, healthy lifestyle, however it also requires effort on your part.
Where do you source your products from?
Please be advised that all of our ingredients, including flavourings, are derived from natural ingredients and are ISURA tested & certified (in order to ensure the absence of GMOs, contaminants, heavy metals and adulteration). All of our products are manufactured at a GMP facility certified by Health Canada. All raw materials come in and are tested for purity, safety and potency. If they do not meet our standards they are rejected and sent back or destroyed. We use the highest quality ingredients available, and choose organic whenever we can. Many of our products contain proprietary patented ingredients that have been clinically researched to help deliver optimal results and outstanding quality.Are your products peanut free?
Following compliance with food regulations, in order to make a negative claim such as "peanut free", it would be necessary to insure a zero tolerance of any peanut traces, including the possibility of cross contamination. Although our manufacturing facility has a policy in place for allergen control, there is no specific policy for peanuts, nor is there a specific "no peanut agreement" with our raw material suppliers.Can your products be used after the expiry date has passed?Supplements generally keep their potency long after the expiry date. There is certainly no safety issues with consuming after the expiry date has passed however the potency degrades over longer periods of time.If a product does not specify "vegetarian capsule", then what is it made from?These capsules are gelatin capsules sourced from either pork or beef.Are any of your products "vegan-friendly"?
Yes, AdrenaSense, EstroSense, MenoSense, BioSil, Medi-C Plus, Magnesium and MagSense (from our WomenSense and Preferred Nutrition product lines), the Healing Teas, our Ultimate Maca Energy products and the Ultimate VEGAN line are all vegan friendly.
Why can't I find any prices on your website?
Preferred Nutrition is the wholesale distribution company for the products on this website. However we sell exclusively to Health Food stores & selected Natural Pharmacies across Canada, not directly to the general public. Because the prices of our products can vary from store-to-store, we are unable to list our suggested prices on our website. We recommend you contact your local retailer and inquire about prices directly with them. Can I purchase products directly from you? I went to a health food store and the prices seem very expensive.We distribute our products in Canada only and we sell directly to Health Food stores - since they have a personal commitment to the natural health lifestyle. Consumers are then able to buy our products from knowledgeable staff that are genuinely interested in helping people be well - people who care! Always be sure to look for in store promotions or coupons when you are making your purchases as this can help alleviate your cost concerns.Do all health food stores carry all of your products?To find Health Food stores in your area that carry our products, please click on "Store Locator" at the top of this screen. All you have to do is enter your postal code and you will be given a list of retailers in the radius that you choose. We do recommend calling ahead to see if they stock the item you are looking for and in most cases if a store does not normally carry something, they will offer to do a special order for you.Are any of your products tested on animals?
No, there is no animal testing on any of our products.Should your supplements be taken with or without food?
Most of our products will specify directly on the bottle whether they should be taken with a meal or not. If nothing is stated, then the choice is yours as to when the best time is for you to take them. In general, however, most vitamin supplements should be taken with food because once eating starts the digestive process, enzymes and gastric juices are generated and usually the nutrients will be absorbed and assimilated better.I like the sound of many of your products. Am I able to take different formulas at the same time?Yes, it's safe to combine various WomenSense products to help support the body in achieving optimal health. The same applies to the Preferred Nutrition line, Dr. Whitaker's formulas and Brad King's. If you are unsure of any combination, then please consult your Health Care Practitioner.I have heard that drinking green tea along with my supplements will end up flushing out all the nutrients? Is this true?No, you are fine taking your supplements with green tea. Coffee inhibits the absorption of nutrients, but the caffeine in green tea will not pose the same problem.Can you tell me if I can combine any of your supplements with the medication(s) I am on, as prescribed by my doctor?It is best to consult your Doctor or alternative Health Practitioner before taking any new supplements while on prescribed medication. If you have been approved to add our supplement(s) to your daily regime, then we do recommend that you space the medication and the supplements out by at least one hour.Can I take your products when I am pregnant or breastfeeding?We are not able to make any recommendations with any of our products when it comes to pregnancy or while nursing. You must contact your Health Practitioner, Naturopath or Pharmacist.I understand that you put a recommended dosage on your labels, but I can take more or less than that, right? And, really, do I have to take the product every day?With regards to the recommended dosage, we would suggest you speak to your Doctor or Health Care Practitioner before increasing any amounts. As with any supplement you can determine your amount based on your personal preference - if you find that a product works for you immediately then you should be fine to take it just on the days you feel you need it, but again we suggest you discuss this with you MD or HP. Some consumers find that a product needs to be in their system for a few days to a few weeks before they notice results and/or feel the full benefits.
I don't understand why when I purchase your product and open the bottle, the contents don't even fill 1/2 of the packaging that is being used?
The containers we use are determined based on product fill and required label information, as well as capsule count when/where applicable. Sometimes we do have to use a larger bottle than seems necessary because of the information required on the labels - requirements both from Health Canada and in order for the label to be clear and legible to our consumers. Also, in a case where we are offering larger volume (ie/ 400g versus 200g or 180 capsules versus 90 capsules), then we have to put the contents in a bigger container in order for there to be differentiation on the shelf.
I bought a bottle of your product, and although it seemed to feel lighter than usual, I didn't think much of it, until I opened the bottle and discovered that there is nowhere near the amount of capsules inside as there should have been. How can this happen?
As part of our corporate policy and Good Manufacturing Practices (GMP) requirement, our procedures incorporate routine in-process checks plus a final examination of the finished product to ensure conformance to all aspects of quality, including correct product count. There are a number of checks and balances performed by both Production and Quality Assurance personnel prior to, during, and after the packaging operations to ensure that product under-counts do not happen. Although product under-counts can happen, this occurrence is rare. Should you discover that your bottle is far below the label claim count upon opening - we recommend you return it to your point of purchase as per our 100% customer satisfaction guarantee.
What is your 100% money-back (customer satisfaction) guarantee?
Our 100% money-back/customer satisfaction guarantee ensures that if a customer is not completely satisfied with their purchase, they can return the unused portion of the product (in its original packaging) back to their point of purchase and we will credit the Health Food store 100% of their purchase price from us. We cannot dictate if a store will give cash back or an in-store credit, nor can we override store policies already in place ~ but we do promise to credit them, regardless of the reason for the return.
1. Herschorn, S., Gajewski, J., Schultz, J., et al. (2008). A population-based study of urinary symptoms and incontinence: the Canadian Urinary Bladder Survey. BJU International, 101(1), 52–58.
2. Ashton-Miller, J.A., Howard, D., & DeLancey, J.O. (2001). The functional anatomy of the female pelvic floor and stress continence control system. Scand J Urol Nephrol Suppl, (207), 1-7; discussion 106-25.
3. Damiano, R., Cai, T., Fornara, P., et al. (2016). The role of Cucurbita pepo in the management of patients affected by lower urinary tract symptoms due to benign prostatic hyperplasia: A narrative review. Archivio Italiano di Urologia e Andrologia, 88(2), 136-143.
4. Widy-Tyszkiewicz, E., Matlawska, I., & Bylka, W. (2012). Assessment report on Cucurbita pepo L., semen. European Medicines Agency. EMA/HMPC/136022/2010.
5. American Botanical Council. (2000). Herbal Medicine: Expanded Commission E Monographs. Pumpkin Seed. Retrieved from http://cms.herbalgram.org/expandedE/ Pumpkinseed.html
6. Shim, B., Jeong, H., Lee, S., et al. (2014). A randomized double-blind placebo-controlled clinical trial of a product containing pumpkin seed extract and soy germ extract to improve overactive bladder-related voiding dysfunction and quality of life. Journal of Functional Foods, 8, 111-117.
7. Yanagisawa, E., & Satoh, I. (2003). Translated from Japanese: Study of effectiveness of mixed processed food containing Cucurbita pepo seed extract and soybean seed extract on stress urinary incontinence in women. Japanese Journal of Medicine and Pharmaceutical Science, 14(3), 313-322.
8. Leibbrand, M., Siefer, S., Schön, C., et al. (2019). Effects of an oil-free hydroethanolic pumpkin seed extract on symptom frequency and severity in men with benign prostate hyperplasia: A pilot study in humans. Journal of Medicinal Food, 22(6), 551-559. 9. Carbin, B.E., Larsson, B., & Lindahl, O. (1990). Treatment of benign prostatic hyperplasia with phytosterols. British Journal of Urology, 66(6), 639-641.
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