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EstroSense

EstroSense

WomenSense

EstroSense®

HORMONE BALANCE FORMULA

What to expect from this product:

  • Supports healthy hormone balance (estrogen to progesterone)
  • Supports healthy breasts
  • Detoxifies the liver of xenoestrogens
  • Reduces flooding and heavy periods
  • Helps those with PCOS and ovarian cysts
  • Inhibits conversion of 2-hydorsyestrone metabolites to carcinogenic estrogens (16-hydroxyestrone)
  • Cancer-protecting plant nutrients
  • Reduces PMS symptoms
  • Supports normal PAP smears
  • Helps reduce endometriosis and fibroids

Symptoms of hormone imbalance are sparked by an imbalance of estrogen to progesterone, with estrogen being dominant. It is important to understand that there are several different forms of estrogen, with some being beneficial and others being potentially harmful.1 For example, synthetic estrogens present in the environment are called xenoestrogens. These toxins are found in pesticides and other chemicals and exposure to these chemicals can result in imbalanced hormone levels, menstrual cycle disruption, reduced fertility and a range of other possible effects.2 

Even among the body’s naturally produced hormones, there are harmful and beneficial estrogens. Extensive research in animals and in humans has shown that higher levels of one form of estrogen, called 2-hydroxyestrone is associated with a reduced risk of breast cancer in women, whereas higher levels of another form, called 16α-hydroxyestrone, has been associated with a significantly increased risk of breast cancer.1,3 

It is clear then that shifting the balance of estrogen in the body towards the “good” form of estrogen is highly desirable and can have many beneficial health effects. EstroSense® is a complete natural formula that helps to maintain lifelong healthy hormone balance from puberty onward. EstroSense® contains an effective combination of ingredients that have been clinically demonstrated to help promote healthy estrogen metabolism, detoxification of harmful chemicals and hormones, and the production of beneficial estrogen hormones. 

EstroSense®  is the ideal hormonal health partner for women using oral contraceptives and those suffering from various symptoms of hormonal imbalance which could include, breast health concerns, exposure to xenoestrogens (pesticides, herbicides and toxins), endometriosis, fibrocystic breasts, heavy/flooding periods, PMS, ovarian cysts, uterine fibroids and more.

Calcium-D-Glucarate – D-glucarate is a naturally occurring substance that is found in many fruits and vegetables. D-glucarate has been shown to help enhance the detoxification of toxins and carcinogens in the body. It also enhances estrogen metabolism, helping to promote healthy hormone balance.4,5

Indole-3-Carbinol – I3C is a compound found in broccoli and other cruciferous vegetables that has been shown to promote healthy estrogen metabolism in women by helping to shift the balance of estrogen in the body towards 2-hydroxyestrone, the “good” form of estrogen.6 As a result, I3C can help to improve hormone balance and may also help to reduce the risk of estrogen-related cancers, like breast and cervical cancer.6 I3C has also been used successfully as a treatment in women with cervical dysplasia.6

Broccoli Extract: Sulforaphane – Sulforaphane is another detoxification compound found in broccoli. Sulforaphane is a powerful antioxidant that can help to enhance the immune system and improve the body’s ability to detoxify and eliminate harmful chemicals and hormones.7,8 Preliminary studies also suggest that sulforaphane may be able to target and destroy early breast cancer cells.8  

Milk Thistle Extract – Milk Thistle is known for its liver protecting properties. This natural antioxidant works together with sulphoraphane to enhance the function of the liver, improving its ability to eliminate toxins, excess hormones and harmful forms of estrogen.9 As a result, healthy estrogen balance is restored, and side-effects of unbalanced hormone levels can be reduced. 

Additional Antioxidants – EstroSense also contains a combination of other powerful natural antioxidants that work together to protect the body’s cells and tissues from damage, reduce inflammation and the risk of disease and help to maintain hormone balance. These antioxidants include rosemary extract, green tea extract, turmeric and lycopene. Green Tea extract, for example, has been shown to support estrogen balance, with one study showing that green tea drinkers have lower blood estrogen levels than non-drinkers.10

EACH CAPSULES CONTAINS

Medicinal Ingredients
  • Calcium D-Glucarate… 75 mg
  • Indole-3-Carbinol (plant sourced)… 75 mg
  • Green Tea Extract (80% Polyphenols)… 50 mg
    (30:1 from 3000 mg of Green Tea–caffeine free)
  • Turmeric (95% Curcumin) … 25 mg
  • Milk Thistle Extract (80% Silymarin)… 25 mg
    (30:1 from 1500 mg of Milk Thistle)
  • Rosemary Extract (6% Carnosic Acid)… 12.5 mg
    (10:1 from 250 mg of Rosemary)
  • Lycopene (from 83 mg Lyc-O-Mato® tomato extract)… 2.5 mg
  • Sulforaphane… 100 mcg
    (from Broccophane™ broccoli sprout extract)

Encapsulated in a vegetarian capsule, microcrystalline cellulose (cellulose, purified water, silica), L-Leucine, silica.

3 capsules daily taken with food or as directed by a health care practitioner.

I have a new bottle of EstroSense and I see that the ingredient DIM has been removed.  Can you tell me why?

DIM was removed from EstroSense because the NHPD (Natural Health Products Directorate) concluded that there was not enough safety evidence for this ingredient in humans to support its inclusion in the formula.  Rest assured the removal of DIM will not change the benefits and effectiveness of EstroSense.  I-3-C remains in the product and this ingredient offers the same benefits as DIM, as they both have essentially the same action and effect in the body.  (I-3-C is a compound found in broccoli and other cruciferous vegetables that has been shown to promote health estrogen metabolism in humans, thereby helping to reduce the risk of estrogen-related cancers). 

Why does my new bottle of EstroSense smell so bad?

The strong smell of EstroSense comes from the glucosinolates, which are sulfur-containing compounds found in cruciferous vegetables - which in EstroSense are the indole-3-carbinol and the sulforaphane.  Remember that all the ingredients used in our products are only sourced from the highest quality suppliers available, always meet the quality standards established by Natural Health Product Directorate (NHPD) and the noticeable variations in the smell of EstroSense can be attributed to the inherent smell of the raw material ingredients used in the product’s formulation.

Why is there a caution on your EstroSense labels about low iron levels?

The iron deficiency caution on our new EstroSense label is derived from the Green Tea Extract Monograph (which can be found on the Health Canada website).  The new Health Canada regulations for NPNs require that we make reference to any and all cautions pertaining to the applicable monographs.

What is it about the Green Tea Extract that can affect iron absorption?

Green tea contains tannins that may affect iron absorption by forming a complex with the iron in the digestive tract and the resulted complex is not bio-available (only plant sources of iron are affected by tannins). 

What is "Sulforaphane"? Does it have anything to do with Sulpha drugs?

Our Sulforaphane is naturally occurring in broccoli and is obtained from broccoli. It has nothing to do with sulfa drugs.

Is the broccoli sprout extract in BroccoPhane non-GMO?

Yes, we have confirmation on file that this ingredient is non-GMO.

Is Lycopene (Lyc-O-Mato) from real tomato or synthetic?

Lycopene is naturally sourced from non-GMO tomatoes.

I am on the birth control pill. Can I still take EstroSense?

Absolutely, EstroSense should be taken while on the pill. This product protects women from the negative effects of the pill by helping to protect the liver from converting your estrogens into cancer causing estrogens. EstroSense does not lower or reduce the effectiveness of the pill for birth control.

Should I continue to take EstroSense while I have my period, or do I stop like I do with my birth control pill?

Yes, continue to take EstroSense during your period.

I have been on contraceptive pills for many years and am considering stopping.  Is it wise to take EstroSense if I do stop taking the pill?

EstroSense will help while on the pill by metabolizing the hormone by-products and converting them into friendlier compounds.  EstroSense will definitely be essential to take once an individual comes off the pill in order to help keep the liver strong and detoxify the many years of birth control hormones from the body.

Does EstroSense contain soy?

No, this product is soy free.

I see that EstroSense contains milk thistle, but isn't milk thistle estrogenic?

We use milk thistle seed extracts in EstroSense and no, this is not an estrogenic ingredient - it is a very safe herb that can help your liver detoxify cancer causing estrogens.

How much elemental calcium (if any) is in the 150mg dosage of Calcium D-Glucarate that is in each EstroSense capsule?

Calcium D-Glucarate contains 16.15% calcium, therefore each capsule of EstroSense contains 12mg of elemental calcium (or 36mg per 3 capsule dose).

Who should take EstroSense?  Do I stop when I reach menopause?

Any female from the time she gets her first menstrual cycle and right through menopause, should be taking EstroSense.  Even if a woman has stopped menstruating, she will still be exposed on a daily basis to exogenous estrogens from the environment and may still have "bad" estrogens stored in the body's fatty tissue.  Also, many post-menopausal women do take HRT - which, like the birth control pill, has negative side effects that EstroSense can help counteract.

Your label doesn't specify what time of day I should take these capsules?

As long as you are taking the recommended dosage (based on the condition you are trying to address) within a 12-hour day, then it really doesn't matter what time you take them. Many seem to prefer to take 1 capsule with each meal - breakfast, lunch and dinner. If someone would rather take all 3 capsules at once, that is fine too.

How long before I notice a difference by using EstroSense?

EstroSense was designed to help ensure that your hormones are balanced, to help halt ovarian pain and to help alleviate your PMS symptons while normalizing your periods. You should notice EstroSense working within two to three menstrual cycles.

I have started taking EstroSense, but am now experiencing cramps and mid-cycle bleeding.  What could be happening?

EstroSense is important for supporting the liver and detoxification of unhealthy estrogens as well as helping to reduce inflammation.  If the liver is very congested then, in some cases, people may experience a cycle with increased cramping as the body is detoxifying.  If you are taking the full recommended dosage of EstroSense, you might want to consider minimizing your dosage in order to support a gentler detoxification.  If your cramping and mid-cycle bleeding persist, you should see your GP or ND and request an ultrasound, in order to determine what other possible underlying factors are at play.

I have to take an over-the-counter anti-inflammatory just before and then during my period.  Can EstroSense help instead?

PMS and menstrual cramping usually involve inflammation caused by estrogen dominance.  Our EstroSense formula includes herbs to help support healthy metabolism of excess estrogens through the liver and to balance the body's estrogen/progesterone ratio.  Continue to take EstroSense during your period and over time you may not even have to take the anti-inflammatory anymore.

I am currently using Wild Yam cream. Can I use EstroSense also?

Yes, Wild Yam cream and EstroSense can be taken together.

Can I take EstroSene if I am taking Tamoxifin?

EstroSense should be fine to take with Tamoxifen.  Many of the ingredients in EstroSense can actually help minimize the side effects of the Tamoxifen.  The milk thistle seed extract and turmeric can help protect the liver from the ill effects of the drug, plus the antioxidants (lycopene, rosemary, green tea) can help protect recurrence of cancer and protect healthy cells.  Studies have also shown that indole-3-carbinol can actually help to assist Tamoxifin in reducing breast cancer recurrence without interfering with its effectiveness.

Is it safe to take EstroSense and Vitex together?

Yes, we recommend taking these two supplements together to possibly help with fertility issues, as well as with concerns regarding painful periods and heavy bleeding.  Vitex also supports natural progesterone production in the body and by combining this with EstroSense the body's estrogen and progesterone levels can be brought back into balance.

Can I take EstroSense and MenoSense together?

Yes you can, because ultimately EstroSense and MenoSense do different things:  EstroSense works directly with the liver to eliminate bad estrogens and help balance hormones; and MenoSense was developed to specifically help alleviate menopausal symptoms (such as hot flashes and night sweats).

Can men take EstroSense?

Yes, they can.  Just as women can experience estrogen dominance from xenoestrogens (exogenous estrogens from the environment), so can men. Calcium-d-glucarate, Indole-3-carbinol and sulphoraphane all help metabolize excess estrogen from the body through the liver.  Milk thistle and curcumin help support the liver for detoxification.  Lycopene, green tea and rosemary are all potent antioxidants - and all these ingredients are totally safe to be taken by men and are certainly not female specific.

I recently bought a bonus bottle of EstroSense 150 capsules, and I was extremely disappointed in the packaging. The bottle is huge and when you open it, it's only 1/4 full. I don't understand why the bottle has to be so big - isn't this a waste of packaging in the day and age of being environmentally friendly? Why not at least put it in a smaller bottle? 150 capsules are 150 capsules, no matter what size the bottle is.

This has been an ongoing challenge with our bottles. With Canadian label standards it has been difficult to get all the required print on our labels in both English and French while keeping the font large enough that it can be easily read. Also, this is a bonus bottle size which required us to use a larger bottle than the 180's so that there would be no confusion on the shelves at retail level. We have used smaller bottles in the past and have received feedback that the writing was too small and hard to read. We try our best to put our products in the smallest bottle possible in an effort to be mindful of the environment. Thank you for bringing this matter to our attention again as it has prompted us to take another look at our options in this area.

Do all of your products have an NPN?

Yes, all of our products have been issued a Natural Product Number (NPN) by Health Canada – these numbers do appear on our labels.  Further Natural Health Product criteria and information can be found on the Health Canada website www.hc-sc.gc.ca  Under the Food and Drugs Act items that are considered a food – for example, our protein powders and herbal teas – do not require an NPN.  Some of our products are still in the application process or are waiting to be reviewed by Health Canada.

Are your capsules GMO free?

Yes, both our capsule shells and our softgel shells are GMO free.

Why have your cautions and your recommended/suggested usages changed so dramatically on many of your labels?

The changes you may be noticing to our suggested usage and cautionary statements have been at the directive of Health Canada.  There have been many regulatory changes with regards to Natural Health Products causing companies to change their labels accordingly.  We have been updating our website, product information sheets and labels on the actual products to reflect these regulations as quickly as we possibly can.

Where do you source your products from?  

All of our products are manufactured at a GMP facility certified by Health Canada.  All raw materials come in and are tested for purity, safety and potency.  If they do not meet our standards they are rejected and sent back or destroyed.  We use the highest quality ingredients available.  Many of our products contain proprietary patented ingredients that have been clinically researched.  We also use organic whenever we can.

Are your products gluten free?

All of our products are manufactured in a facility that is not dedicated to be gluten free.  Therefore we cannot guarantee that any of our products are gluten free since there is always a possibility of cross-contamination.

Are your products peanut free?

Following compliance with food regulations, in order to make a negative claim such as "peanut free", it would be necessary to insure a zero tolerance of any peanut traces, including the possibility of cross contamination.  Although our manufacturing facility has a policy in place for allergen control, there is no specific policy for peanuts, nor is there a specific "no peanut agreement" with our raw material suppliers.

Can your products be used after the expiry date has passed?

Supplements generally keep their potency long after the expiry date.  There is certainly no safety issues with consuming after the expiry date has passed however the potency degrades over longer periods of time.

If a product does not specify "vegetarian capsule", then what is it made from?

These capsules are gelatin capsules sourced from either pork or beef.

Are any of your products "vegan-friendly"?

Yes, AdrenaSense, BioSil, EstroSense and MenoSense (from our Preferred Nutrition and WomenSense lines), Immuno-Care, our Ultimate Maca Energy products and the Ultimate VEGAN line are all vegan friendly.

Can I purchase products directly from you?  I went to a health food store and the prices seem very expensive.

We distribute our products in Canada only and we sell directly to Health Food stores - since they have a personal commitment to the natural health lifestyle.  Consumers are then able to buy our products from knowledgeable staff that are genuinely interested in helping people be well - people who care!  Always be sure to look for in store promotions or coupons when you are making your purchases as this can help alleviate your cost concerns.

Do all health food stores carry all of your products?

To find Health Food stores in your area that carry our products, please click on "Store Locator" at the top of this screen.  All you have to do is enter your postal code and you will be given a list of retailers in the radius that you choose. We do recommend calling ahead to see if they stock the item you are looking for and in most cases if a store does not normally carry something, they will offer to do a special order for you.

Are any of your products tested on animals?

No, there is no animal testing on any of our products.

Should your supplements be taken with or without food?

Most of our products will specify directly on the bottle whether they should be taken with a meal or not.  If nothing is stated, then the choice is yours as to when the best time is for you to take them.  In general, however, most vitamin supplements should be taken with food because once eating starts the digestive process, enzymes and gastric juices are generated and usually the nutrients will be absorbed and assimilated better.

I like the sound of many of your products.  Am I able to take different formulas at the same time?

Yes, it's safe to combine various WomenSense products to help support the body in achieving optimal health.  The same applies to the Preferred Nutrition line, Dr. Whitaker's formulas and Brad King's.  If you are unsure of any combination, then please consult your Health Care Practitioner.

I have heard that drinking green tea along with my supplements will end up flushing out all the nutrients?  Is this true?

No, you are fine taking your supplements with green tea.  Coffee inhibits the absorption of nutrients, but the caffeine in green tea will not pose the same problem.

Can you tell me if I can combine any of your supplements with the medication(s) I am on, as prescribed by my doctor?

It is best to consult your Doctor or alternative Health Practitioner before taking any new supplements while on prescribed medication.  If you have been approved to add our supplement(s) to your daily regime, then we do recommend that you space the medication and the supplements out by at least one hour.

Can I take your products when I am pregnant or breastfeeding?

We are not able to make any recommendations with any of our products when it comes to pregnancy or while nursing.  You must contact your Health Practitioner, Naturopath or Pharmacist.

I understand that you put a recommended dosage on your labels, but I can take more or less than that, right?  And, really, do I have to take the product every day?

With regards to the recommended dosage, we would suggest you speak to your Doctor or Health Care Practitioner before increasing any amounts.  As with any supplement you can determine your amount based on your personal preference - if you find that a product works for you immediately then you should be fine to take it just on the days you feel you need it, but again we suggest you discuss this with you MD or HP.  Some consumers find that a product needs to be in their system for a few days to a few weeks before they notice results and/or feel the full benefits.  

I bought a bottle of your product, and although it seemed to feel lighter than usual, I didn't think much of it, until I opened the bottle and discovered that there is no where near the amount of capsules inside as there should have been.  How can this happen?

As part of our corporate policy and Good Manufacturing Practices (GMP) requirement, our procedures incorporate routine in-process checks plus a final examination of the finished product to ensure conformance to all aspects of quality, including correct product count.  There are a number of checks and balances performed by both Production and Quality Assurance personnel prior to, during, and after the packaging operations to ensure that product under-counts do not happen. Although product under-counts can happen, this occurrence is rare.  Should you discover that your bottle is far below the label claim count upon opening - we recommend you return it to your point of purchase as per our 100% customer satisfaction guarantee.

What is your 100% money-back (customer satisfaction) guarantee?

Our 100% money-back/customer satisfaction guarantee ensures that if a customer is not completely satisfied with their purchase, they can return the unused portion of the product (in its original packaging) back to their point of purchase and we will credit the Health Food store 100% of their purchase price from us.  We cannot dictate if a store will give cash back or an in-store credit ~ but we do promise to credit them, regardless of the reason for the return.

Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL, Bjeldanes LF (2004) Pilot Study: Effect of 3,3’ – Diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutrition and Cancer, 50(2): 161-167

Lao CD, Ruffin MT, Normolle D, Heath DD, Murray SI, Bailey JM, Boggs ME, Crowel J, Rock CL, Brenner DE (2006) Dose escalation of a curcuminoid formulation. BMC Complimentary and Alternative Medicine, 6:10

Bell MC, Crowley-Nowick P, Bradlow HL, Sepkovic DW, Schmidt-Grimminger D, Howell P, Mayeaux EJ, Tucker A, Turbat-Herrera EA, Mathis JM (2000) Placebo-controlled trial of Indole-3-Carbinol in the treatment of CIN. Gynecologic Oncology, 78: 123-129

Reed GA, Peterson KS, Smith HJ, Gray JC, Sullivan DK, Mayo MS, Crowel JA, Hurwitz A (2005) A Phase 1 study of Indole-3-Carbinol in women: tolerability and effects. Cancer Epidemiol Biomarkers, 14(8): 1953-1960

Walaszek Z, Hanausek M, Narog M, Raich PC, Slaga TJ (2004) Mechanisms of lung cancer chemoprevention by d-Glucarate. Chest, 125:149S – 150S

Chow HHs, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS (2003) Pharmacokinetics and Safety of Green Tea Polyphenols after Multiple-Dose Administration of Epigallocatechin Gallate and Polyphenon E in Healthy Individuals. Clinical Cancer Research, 9: 3312-3319

Cheung CW, Gibbons N, Johnson DW, Nicol DL (2010) Silibinin – a promising new treatment for cancer. Anticancer Agents Med. Chem, 10(3):186-195

Wang HJ, Jiang YY, Wei XF, Huang H, Tashiro S, Onodera S, Ikejima T (2010) Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells. Free Radic Res, 44(1):90 – 100

Kim S, Kim SH, Hur SM, Lee SK, Kim WW, Kim JS, Kim JH, Chloe JH, Nam SJ, Lee JE, Yang JH (2009) Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells. Journal of Ethnopharmacol, 126(2):252-257

Lin CJ, Sukarieh R, Peletier J (2009) Silibinin inhibits translation initiation: implications for anticancer therapy. Molecular Cancer Therapeutics, 8(6): 1606-1612

Kim S, Chol JH, Lim HI, Lee SK, Kim WW, Kim JS, Kim JH, Choe JH, Yang JH, Nam SJ, Lee JE (2009) Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells. Phytomedicine, 16(6-7): 573 – 580

Wang HJ, Tashiro S, Onodera S, Ikejima T (2008) Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells. Journal of Pharmacological Sciences, 107(3): 260-269

Verschoyle RD, Brown K, Steward WP, Gescher AJ (2008) Cpnsumption of silibinin, a flavonolignan from milk thistle, and mammary cancer development in the C3(1) SV40 T,t antigen transgenic multiple mammary adenocarcinoma (Tag)  mouse. Cancer Chemotherapy and Pharmacology, 62(2):369-372

Raina K, Agarwal R (2007) Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms. Acta Pharmacologica Sinica, 28(9):1466-1475

Lee SO, Jeong YJ, Im HG, Kim CH, Chang YC, Lee IS (2007) Silibinin suppresses OMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells. Biochemical and Biophysical Research Communications, 354(1): 165-171

(2009) Milk Thistle [Monograph]. Retrieved from Health Canada Natural Health Products Ingredients Database

(2008) Rosemary – Oral [Monograph]. Retrieved from Health Canada Natural Health Products Ingredients Database

(2008) Turmeric – Oral [Monograph]. Retrieved from Health Canada Natural Health Products Ingredients Database

(2006) Calcium D-Glucarate [Monograph]. Retrieved from Natural Medicines Comprehensive Database

(2006) Lycopene [Monograph]. Retrieved from Natural Medicines Comprehensive Database

(2006) Sulforphane [Monograph]. Retrieved from Natural Medicines Comprehensive Database

References 

1.     Bradlow HL et al. 2-hydroxyestrone: the 'good' estrogen. J Endocrinol. 1996 Sep; 150 Suppl: S259-65.

2.     Degen GH and Bolt HM. Endocrine disruptors: update on xenoestrogens. Int Arch Occup Health. 2000. 73: 433-441.

3.     Muti P et al. Estrogen Metabolism and Risk of Breast Cancer: A Prospective Study of the 2:16α-Hydroxyestrone Ratio in Premenopausal and Postmenopausal Women. Epidemiology, Vol. 11, No. 6 (Nov., 2000), pp. 635-640.

4.     Calcium D-Glucarate Monograph. Alternative Medicine Reviews. 2002. 7(4): 336-339.

5.     Heerdt AS, Young CW, Borgen PI. Calcium glucarate as a chemopreventive agent in breast cancer. Isr J Med Sci 1995;31:101-105.

6.     Reed GA et al. A Phase I Study of Indole-3-Carbinol in women: Tolerability and Effects. Cancer Epidemiol Biomarkers Prev. 2005; 14(8): 1953-1958.

7.     Kim Hj et al. Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells. The Journal of Allergy and Clinical Immunology. 2008; 121(5): 1255-1267.

8.     Li Y et al. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Cancer Res. 2010 May 1;16(9):2580-90

9.     Prdahan SC and Girish C. Hepatoprotective Herbal Drug, Silymarin From Experimental Pharmacology to Clinical Medicine. Indian Journal of Medical Research. 2006.

10.  Wu AH et al. Tea and Circulating Estrogen Levels in Postmenopausal Chinese Women in Singapore. Carcinogenesis.May 2005.

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