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Medi-C Plus
Medi-C Plus

Medi-C Plus Where-to-buy2015

Vitamin C & Lysine Formula

NPN 80035260/80040799/80069904

What to expect from this product:

  • Supports cardiovascular health and immune function
  • Helps support collagen formation
  • Helps reduce the recurrence of cold sores
  • Helps maintain bones, teeth, and gums
  • Provides a key antioxidant
  • Buffered with calcium or magnesium to reduce gastrointestinal upset

Vitamin C (ascorbic acid) is an essential water-soluble vitamin needed by the body for a wide range of important processes. These include supporting immune system activity and collagen synthesis. Collagen is the body’s most abundant protein and is a key component of blood vessels, joint tissue, and skin, where it provides structure, strength, and elasticity. Vitamin C and lysine work together to build collagen, strengthening and holding together the coronary cells (Sommer et al., 2007). Coronary arteries, closest to the heart, receive the most significant pressure. Without enough vitamin C, the collagen weakens. Healthy collagen also supports healthy teeth, gums, cartilage, bones, connective tissue, and wound healing.

There is some evidence that lysine modifies pathways that lead to vascular calcification, which is where plaques build up in arteries, affecting cardiovascular health (Shimomura et al., 2014). Vitamin C and lysine are also among several natural compounds seen to have anti-atherogenic effects on the smooth muscle cells in the walls of arteries (Ivanov et al., 2007).

Vitamin C’s antioxidant activity and role in creating healthy connective tissue also positively impacts the cardiovascular system. In a randomized, double-blind, placebo-controlled trial, 31 patients who received at least 500 mg of vitamin C daily had decreases in both mean systolic blood pressure and diastolic blood pressure after a month (Hajjar et al., 2002). Conversely, vitamin C deficiency is related to lower levels of high-sensitivity C-reactive protein (hsCRP), an inflammatory biomarker that predicts cardiovascular disease (Song & Kang, 2018).

Vitamin C helps maintain normal immune function by increasing T-lymphocyte activity, leukocyte mobility, and antibody and interferon production (Leibovitz & Siegel, 1981; Kasa, 1983). There is some evidence that taking 600–1000 mg of vitamin C per day for 3–8 weeks before intense physical exercise, such as a marathon, can significantly reduce the risk of upper respiratory tract infections (Moreira et al., 2007; Hemilä, 1996).

Low vitamin C status has been seen in cases of community-acquired pneumonia. A medical assessment of 50 people with community-acquired pneumonia classified 62% with hypovitaminosis C (plasma levels at 5–15 mg/L) and 22% as being vitamin C deficient. In comparison, healthy controls had a rate of 8% hypovitaminosis C and no deficiencies. Pneumonia patients were also found to have elevated levels of oxidative stress (Carr et al., 2020).

The body’s need for vitamin C increases during times of stress, such as intense physical activity, illness, antibiotic use, and exposure to pollutants. Multiple studies have found a correlation between low vitamin C levels and higher rates of oxidative stress, an underlying factor in many forms of illness. Specifically, low vitamin C levels and oxidative stress have been linked to impaired immunity and increased susceptibility to infection (Carr et al., 2020; Paschalis et al., 2016).

Lysine is an essential amino acid, meaning that it must be obtained through the diet or supplements as the body cannot manufacture it. As a major building block of many proteins in the body, including collagen and enzymes involved in immunity, lysine deficiency can quickly have serious consequences (Yamauchi & Sricholpech, 2012). In the 1980s, a wealth of studies examined the effects of lysine on the herpes simplex virus-1 (HSV-1) that causes cold sores. In one double-blind, placebo-controlled study, 41 participants were given 1248 mg of lysine per day and experienced a decrease in the frequency and severity of cold sores; a lower dose of 624 mg did not prove effective (McCune et al., 1984).

Calcium is a major structural component of healthy bones and teeth and is needed for the contraction of muscles, including the heart and blood vessels, to maintain healthy blood pressure (McEvoy, 1998). Long-term calcium supplementation in postmenopausal women has been shown to reduce the incidence of spinal fracture by 30–35% and lower hip fracture rates by 25% (Kanis, 1999).

Each 6.5 cc level scoop (5 g) contains:
Vitamin C (magnesium ascorbate, ascorbic acid) ..............2000 mg
Magnesium (magnesium ascorbate) .................................210 mg
L-lysine (L-lysine hydrochloride) .....................................1300 mg

Non-medicinal ingredients: Natural flavours, citric acid, Stevia rebaudiana leaf, Oryza sativa (rice) hull powder.

This product does not contain artificial preservatives, colours, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.


Each vegetarian capsule contains:
Vitamin C (magnesium ascorbate, ascorbic acid) .................400 mg
Magnesium (magnesium ascorbate) ................................... 42 mg
L-Lysine (L-lysine hydrochloride) ...................................... 260 mg

Non-medicinal ingredients: Vegetarian capsule (cellulose, purified water), vegetable grade magnesium stearate (lubricant), microcrystalline cellulose, silica.

This product does not contain artificial preservatives, colours, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Caution: Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Keep out of reach of children.

Powder Form:
Recommended adult dose:
Dissolve one level 6.5 cc scoop (5 g) daily in 250 mL of water or juice. Stir and drink immediately. Please keep desiccant in container after opening.

Capsule Form:
Recommended adult dose:
5 capsules once daily with food or as directed by a health care practitioner.


Carr, A.C., Spencer, E., Dixon, L., et al. (2020). Patients with community acquired pneumonia exhibit depleted vitamin C status and elevated oxidative stress. Nutrients, 12(5), 1318.

Hajjar, I.M., George, V., Sasse, E.A., et al. (2002). A randomized, double-blind, controlled trial of vitamin C in the management of hypertension and lipids. Am J Ther, 9(4), 289-93.

Hemilä, H. (1996). Vitamin C and common cold incidence: A review of studies with subjects under heavy physical stress. Int J Sports Med, 17(5), 379-8.

Ivanov, V., Roomi, M.W., Kalinovsky, T., et al. (2007). Anti-atherogenic effects of a mixture of ascorbic acid, lysine, proline, arginine, cysteine, and green tea phenolics in human aortic smooth muscle cells. J Cardiovas Pharmacol, 49(3), 140-5.

Kanis, J.A. (1999). The use of calcium in the management of osteoporosis. Bone, 24(4), 279-90.

Kasa, R.M. (1983). Vitamin C: From scurvy to the common cold. Am J Med Technol, 49(1), 23-6.

Leibovitz, B., & Siegel, B.V. (1981). Ascorbic acid and the immune response. Adv Exp Med Biol, 135, 1-25.

McCune, M.A., Perry, H.O., Muller, S.A., et al. (1984). Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis, 34(4), 366-73.

McEvoy, G.K. (Ed.). (1998). AHFS drug information. American Society of Health-System Pharmacists.

Moreira, A., Kekkonen, R.A., Delgado, L., et al. (2007). Nutritional modulation of exercise-induced immunodepression in athletes: A systematic review and meta-analysis. Eur J Clin Nutr, 61(4), 443-60.

Paschalis, V., Theodorou, A.A., Kyparos, A., et al. (2016). Low vitamin C values are linked with decreased physical performance and increased oxidative stress: Reversal by vitamin C supplementation. Eur J Nutr, 55(1), 45-53.

Shimomura, A., Matsui, I., Hamano, T., et al. (2014). Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol, 25(9), 1954-65.

Sommer, F., Kobuch, K., Brandl, F., et al. (2007). Ascorbic acid modulates proliferation and extracellular matrix accumulation of hyalocytes. Tissue Eng, 13(6), 1281-9.

Song, E.K., & Kang, S.M. (2018). Vitamin C deficiency, high-sensitivity C-reactive protein, and cardiac event-free survival in patients with heart failure. J Cardiovas Nurs, 33(1), 6-12.

Yamauchi, M., & Sricholpech, M. (2012). Lysine post-translational modifications of collagen. Essays Biochem, 52, 113-33.

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